NIH-funded research R21 grant

Effects of teenage drinking on behavior later in life

Official title: Long term consequences of adolescent alcohol use on behavioral inhibition

Funded at Oregon Health & Science University · NIH-10831949 · Data updated 2026-11-12

This study looks at how drinking alcohol during the teenage years might change behavior as adults, especially in terms of being impulsive and controlling responses, using a rodent model to explore how the brain works in these situations.

More Alcohol Use research and trials

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionOregon Health & Science University
NIH-funded
Lab location1 site (Portland, United States)
Project startMay 1, 2023
Project endApril 30, 2026
Funding year2024
Award (this year)$182,875
NIH project number5R21AA030141-02
Project IDNIH-10831949 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adolescents aged 12-20 who have engaged in alcohol consumption.

Less likely to help

Patients who have not consumed alcohol during adolescence or who are outside the age range of 12-20 may not benefit from this research.

What this research studies

This research investigates how voluntary alcohol consumption during adolescence affects behavior in adulthood, particularly focusing on impulsivity and response inhibition. Using a rodent model, the study aims to understand the neuronal mechanisms involved by examining brain regions associated with decision-making and impulse control. The researchers will record brain activity during specific tasks and manipulate neural connections to explore how these factors contribute to behavioral changes. This work seeks to provide insights into the long-term consequences of adolescent drinking.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for impulsive behaviors linked to early alcohol use.

How similar studies have gone: Previous research has indicated that adolescent alcohol use can lead to lasting behavioral changes, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Oregon Health & Science University
    Portland, United States
    Active

Researchers

  • Principal investigator: Moghaddam, Bita — Oregon Health & Science University
  • Study coordinator: Moghaddam, Bita

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.