Effects of synthetic progestin on brain development and behavior
Cortical and Cognitive Development Following Synthetic Progestin Exposure
This study is looking at how a certain synthetic hormone given during pregnancy might affect the brain development and thinking skills of babies, using rodent models to see how it impacts attention and behavior later in life.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | State University of New York at Albany NIH-funded |
| Lab location | 1 site (Albany, United States) |
| Project ID | NIH-10441462 on NIH RePORTER |
What this research studies
This research investigates how exposure to synthetic progestins during pregnancy affects brain development and cognitive functions in offspring. Using rodent models, the study will analyze the impact of a specific synthetic progestin on the development of critical brain pathways associated with attention and behavior. The research will employ advanced techniques like high-performance liquid chromatography and mass spectrometry to measure hormone levels and assess changes in brain structure and function. Ultimately, the study aims to understand how these hormonal exposures may influence cognitive abilities and behaviors in later life.
Who could benefit from this research
Good fit: Ideal candidates for this research are pregnant women who may be prescribed synthetic progestins to prevent premature delivery.
Not a fit: Patients who are not pregnant or those who have not been exposed to synthetic progestins during pregnancy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive and behavioral issues related to prenatal exposure to synthetic progestins.
How similar studies have performed: Previous studies using rodent models have shown that hormonal exposure can significantly affect brain development, suggesting that this research builds on established findings.
Where this research is happening
Albany, United States
- State University of New York at Albany — Albany, United States (Active)
Researchers
- Principal investigator: Wagner, Christine K — State University of New York at Albany
- Study coordinator: Wagner, Christine K
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.