Effects of sugary drinks on gut health and young-onset colorectal cancer
Impact of sugary drinks on gut microbiota and development of young-onset colorectal cancer
This study is looking at how drinking sugary drinks might be linked to an increase in colorectal cancer in people under 50, using mice to see if these drinks speed up the growth of early cancer signs, and it hopes to find ways that changing our diets could help prevent this type of cancer in younger folks.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Tx Md Anderson Can Ctr NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10734338 on NIH RePORTER |
What this research studies
This research investigates the potential link between the consumption of sugar-sweetened beverages (SSBs) and the rising rates of colorectal cancer in individuals under 50. By using a mouse model that mimics early-stage colon cancer, the study aims to understand how SSBs may accelerate the development of precancerous polyps into cancer. The researchers will explore the role of diet in shaping gut microbiota and how an unhealthy diet may contribute to cancer development. This could provide insights into dietary interventions that may help prevent young-onset colorectal cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are young adults under 50 who consume sugar-sweetened beverages regularly.
Not a fit: Patients who do not consume sugar-sweetened beverages or who are over 50 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to dietary recommendations that help reduce the risk of colorectal cancer in young adults.
How similar studies have performed: Previous studies have shown a correlation between diet and colorectal cancer, but this research aims to establish a direct causal link, making it a novel approach.
Where this research is happening
Houston, United States
- University of Tx Md Anderson Can Ctr — Houston, United States (Active)
Researchers
- Principal investigator: Yun, Jihye — University of Tx Md Anderson Can Ctr
- Study coordinator: Yun, Jihye
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.