Effects of Semaglutide on Diabetes and Weight Loss in People with Spinal Cord Injury

Glycemic and Weight Loss Effects of Semaglutide in Subjects After Spinal Cord Injury and Type 2 Diabetes

NIH-funded research University of Texas Hlth Science Center · NIH-11179324

This study is looking at how well semaglutide, a medication that helps with blood sugar control and weight loss, works for people with spinal cord injuries who also have type 2 diabetes, to see if it can help them manage their diabetes better.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Hlth Science Center NIH-funded
Lab location1 site (San Antonio, United States)
Project IDNIH-11179324 on NIH RePORTER

What this research studies

This research investigates how semaglutide, a medication that helps control blood sugar and promote weight loss, can benefit individuals with spinal cord injuries who also have type 2 diabetes. The study aims to understand the effectiveness and safety of this treatment in a population that experiences diabetes at a higher rate than those without spinal injuries. By focusing on this specific group, the research seeks to address health disparities and improve diabetes management strategies. Participants will receive semaglutide and be monitored for changes in their blood sugar levels and weight over the course of the study.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals with spinal cord injuries who have been diagnosed with type 2 diabetes.

Not a fit: Patients without spinal cord injuries or those who do not have type 2 diabetes may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved diabetes management and weight loss for patients with spinal cord injuries.

How similar studies have performed: Previous research has shown that GLP-1 receptor agonists like semaglutide are effective in managing diabetes in the general population, but this specific application in spinal cord injury patients is novel.

Where this research is happening

San Antonio, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions adult onset diabetesAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.