Effects of prenatal exposure to vaping on newborn lung health
Official title: Impact of prenatal exposures to copper from electronic nicotine delivery system (ENDS) aerosols on the immature neonatal pulmonary immune system and IL-10-mediated asthmatic responses
Funded at Louisiana State Univ A&m Col Baton Rouge · NIH-11027001 · Data updated 2026-11-12
This study looks at how breathing in vapor from e-cigarettes during pregnancy might affect babies' lungs and immune systems, especially focusing on the role of copper, to see if it could increase the chances of developing allergies or asthma later on.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Louisiana State Univ A&m Col Baton Rouge NIH-funded |
| Lab location | 1 site (Baton Rouge, United States) |
| Project start | March 18, 2025 |
| Project end | January 31, 2030 |
| Funding year | 2025 |
| Award (this year) | $450,000 |
| NIH project number | 1R01HL176980-01 |
| Project ID | NIH-11027001 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant women who use electronic nicotine delivery systems and their newborns.
✕Less likely to help
Patients who are not pregnant or whose infants are older than four weeks may not benefit from this research.
What this research studies
This research investigates how exposure to electronic nicotine delivery system (ENDS) aerosols during pregnancy affects the developing lungs of newborns. It focuses on the impact of copper, a common metal found in ENDS aerosols, on the neonatal immune system and its potential to increase the risk of allergic asthma. By studying the biological mechanisms involved, the research aims to understand how these exposures may lead to long-term respiratory issues in infants. The study employs a combination of epidemiological data and animal models to explore these effects.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and prevention strategies for asthma and respiratory issues in infants exposed to vaping during pregnancy.
How similar studies have gone: Previous research has indicated potential health risks associated with prenatal exposure to vaping, but this specific investigation into copper's role is relatively novel.
Where this research is happening
-
Louisiana State Univ A&m Col Baton Rouge
Baton Rouge, United States Active
Researchers
- Principal investigator: Noel, Alexandra — Louisiana State Univ A&m Col Baton Rouge
- Study coordinator: Noel, Alexandra
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.