Effects of prenatal alcohol exposure and placental issues on brain development in children
Consequences of combined prenatal alcohol exposure and acute placental ischemia on frontal cortical-sensitive behavior, structure, and physiology in juvenile offspring
This study is looking at how drinking alcohol during pregnancy, along with problems with the placenta, can affect how children think and behave, especially their attention skills, so we can better understand which kids might need extra support as they grow up.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project ID | NIH-10893414 on NIH RePORTER |
What this research studies
This research investigates how prenatal alcohol exposure (PAE) combined with acute placental insufficiency (PI) affects brain development and behavior in children. The study aims to understand the cumulative impact of these two factors on cognitive functions, particularly focusing on attention and behavior. Researchers will use touchscreen testing to assess attention deficits and the ability to control responses in juvenile offspring exposed to both PAE and PI. The findings could help identify children at risk for neurodevelopmental issues due to these prenatal factors.
Who could benefit from this research
Good fit: Ideal candidates for this research include children who were exposed to alcohol in utero and may have experienced placental insufficiency during pregnancy.
Not a fit: Patients who were not exposed to alcohol during pregnancy or did not experience placental insufficiency are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic and prognostic tools for identifying children at risk of neurodevelopmental deficits due to prenatal alcohol exposure and placental insufficiency.
How similar studies have performed: While the individual effects of prenatal alcohol exposure and placental insufficiency have been studied, the combined impact of these factors on brain development is less understood, making this research a novel approach.
Where this research is happening
Albuquerque, United States
- University of New Mexico Health Scis Ctr — Albuquerque, United States (Active)
Researchers
- Principal investigator: Maxwell, Jessie R. — University of New Mexico Health Scis Ctr
- Study coordinator: Maxwell, Jessie R.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.