Effects of prenatal alcohol and methadone on brain development
Impact of prenatal alcohol and methadone exposure on dopamine regulation of BLA plasticity
['FUNDING_R21'] · STATE UNIVERSITY OF NY,BINGHAMTON · NIH-10753305
This study is looking at how being exposed to alcohol and methadone during pregnancy might affect the brain development of babies, especially in how they handle emotions, and it aims to find out if boys and girls are impacted differently.
Quick facts
| Phase | ['FUNDING_R21'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | STATE UNIVERSITY OF NY,BINGHAMTON (nih funded) |
| Locations | 1 site (BINGHAMTON, UNITED STATES) |
| Trial ID | NIH-10753305 on ClinicalTrials.gov |
What this research studies
This research investigates how exposure to alcohol and methadone during pregnancy affects the brain development of offspring, particularly focusing on the dopamine system and its role in emotional regulation. The study aims to understand the combined impact of these substances on the basolateral amygdala, a brain region involved in processing emotions. By examining male and female responses separately, the research seeks to uncover potential differences in how these exposures affect anxiety and emotional processing. Participants may contribute to understanding the neurodevelopmental consequences of prenatal substance exposure.
Who could benefit from this research
Good fit: Ideal candidates for this research include male adolescents and adults who have been exposed to alcohol and/or methadone during pregnancy.
Not a fit: Patients who have not been exposed to prenatal alcohol or methadone are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved interventions and support for children affected by prenatal substance exposure.
How similar studies have performed: Previous research has shown significant effects of prenatal alcohol exposure on neurodevelopment, but the combined effects with methadone are less understood, making this a novel investigation.
Where this research is happening
BINGHAMTON, UNITED STATES
- STATE UNIVERSITY OF NY,BINGHAMTON — BINGHAMTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: DIAZ, MARVIN RAFAEL — STATE UNIVERSITY OF NY,BINGHAMTON
- Study coordinator: DIAZ, MARVIN RAFAEL
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.