NIH-funded research R01 grant

Effects of phthalate exposure on telomeres in unborn babies

Official title: Impact of Phthalate Exposure on Telomere Biology in Utero

Funded at New York University School of Medicine · NIH-11064770 · Data updated 2026-11-12

This study is looking at how chemicals called phthalates, which are found in many everyday products, might affect the health of babies by changing the length of protective parts of their DNA, and it’s for parents who want to understand how these chemicals could impact their child's health as they grow up.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine
NIH-funded
Lab location1 site (New York, United States)
Project startApril 3, 2024
Project endJanuary 31, 2029
Funding year2025
Award (this year)$359,000
NIH project number5R01ES035760-02
Project IDNIH-11064770 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant individuals and their newborns, particularly those with known exposure to phthalates.

Less likely to help

Patients who are not pregnant or whose children are older than 8 years may not benefit from this research.

What this research studies

This research investigates how exposure to phthalates, chemicals found in many everyday products, affects telomere biology in fetuses. It aims to understand whether these chemicals can shorten telomeres in the placenta and newborns, potentially impacting health throughout life. The study will measure telomere length and related biological markers in umbilical cord blood and follow-up samples from children around age 8. By analyzing these samples, researchers hope to uncover the long-term effects of prenatal phthalate exposure on telomere dynamics.

Why it matters

Potential benefit: If successful, this research could lead to better understanding of how prenatal exposures affect long-term health and inform guidelines to reduce harmful exposures during pregnancy.

How similar studies have gone: Previous research has indicated that prenatal exposures can have lasting effects on health, suggesting that this approach may yield valuable insights.

Where this research is happening

  • New York University School of Medicine
    New York, United States
    Active

Researchers

  • Principal investigator: Cowell, Whitney — New York University School of Medicine
  • Study coordinator: Cowell, Whitney

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.