Effects of ovarian hormones on mood and sleep in adolescent girls

Ovarian Steroid Effects on Mood and Sleep Across the Adolescent Menstrual Cycle

NIH-funded research Emma Pendleton Bradley Hospital · NIH-11053826

This study is looking at how changes in hormone levels during the menstrual cycle can affect mood and sleep in girls aged 11-14, to help understand why some may experience more sadness or sleep problems during this time.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionEmma Pendleton Bradley Hospital NIH-funded
Lab location1 site (Riverside, UNITED STATES)
Project IDNIH-11053826 on NIH RePORTER

What this research studies

This research investigates how fluctuations in ovarian steroid hormones during the menstrual cycle affect mood and sleep in adolescent girls aged 11-14. By collecting daily assessments of mood, sleep patterns, and hormone levels from participants, the study aims to understand the relationship between hormone sensitivity and the development of depressive symptoms and sleep issues. The research will utilize advanced statistical models to analyze the data, focusing on those with regular menstrual cycles and elevated depressive symptoms.

Who could benefit from this research

Good fit: Ideal candidates for this research are female adolescents aged 11-14 who are at least one year post-menarche and experience elevated depressive symptoms.

Not a fit: Patients who do not have regular menstrual cycles or who are not experiencing depressive symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment of mood and sleep disorders in adolescent girls.

How similar studies have performed: Previous research has indicated that hormonal fluctuations can impact mood and sleep, suggesting that this approach may yield valuable insights.

Where this research is happening

Riverside, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Affective Disorders
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.