NIH-funded research NIH-funded research

Effects of oral contraceptives and smoking on women's recovery after brain injuries

Official title: Impact of oral contraceptives and smoking on females after traumatic brain injury

Funded at Miami VA Health Care System · NIH-11073031 · Data updated 2026-11-12

This study is looking at how taking birth control pills and smoking might impact recovery for women in the military who have had a mild brain injury, with the goal of finding better ways to help them heal.

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Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMiami VA Health Care System
NIH-funded
Lab location1 site (Miami, United States)
Project startApril 1, 2024
Project endMarch 31, 2028
Funding year2025
NIH project number5I01BX006223-02
Project IDNIH-11073031 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are adult women of childbearing age who have experienced mild traumatic brain injuries and are either smokers or using oral contraceptives.

Less likely to help

Patients who are not women, or those who have not experienced a traumatic brain injury, are unlikely to benefit from this research.

What this research studies

This research investigates how the use of oral contraceptives and smoking affects recovery in women who have experienced mild traumatic brain injury (mTBI), particularly among military servicemembers. The study will explore the biological mechanisms behind these effects, focusing on how these factors may worsen cognitive decline and brain health after injury. By examining the interplay between smoking, oral contraceptive use, and brain metabolism, the research aims to provide insights that could lead to improved care strategies for affected women.

Why it matters

Potential benefit: If successful, this research could lead to better treatment and recovery strategies for women with traumatic brain injuries, particularly those in military service.

How similar studies have gone: Previous research has indicated that the combination of smoking and hormonal factors can negatively impact brain health, suggesting that this study's approach is grounded in established findings.

Where this research is happening

  • Miami VA Health Care System
    Miami, United States
    Active

Researchers

  • Principal investigator: Raval, Ami P — Miami VA Health Care System
  • Study coordinator: Raval, Ami P

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.