Effects of ongoing immune activation in women with HIV on treatment outcomes
Consequences of Persistent Immune Activation among ART-treated Women with HIV
This study is looking at how ongoing immune system activity impacts the health of women with HIV who are on treatment, especially regarding heart and metabolic issues, and it aims to help improve their care during and after COVID-19.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10885055 on NIH RePORTER |
What this research studies
This research investigates how persistent immune activation affects the health of women living with HIV who are receiving antiretroviral therapy (ART). It aims to understand the relationship between immune activation and various health issues, including heart and metabolic diseases, particularly in the context of COVID-19. The study will involve collaboration among experts in HIV medicine, immunology, cardiology, and women's health to gather comprehensive data and insights. Patients may be monitored for immune responses and related health outcomes over time.
Who could benefit from this research
Good fit: Ideal candidates for this research are women living with HIV who are currently receiving ART.
Not a fit: Patients who are not receiving ART or who do not have HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health management strategies for women with HIV, potentially reducing the risk of serious health complications.
How similar studies have performed: Previous research has shown that understanding immune activation in HIV can lead to significant advancements in treatment approaches, indicating a promising avenue for this study.
Where this research is happening
Boston, United States
- Massachusetts General Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Zanni, Markella V. — Massachusetts General Hospital
- Study coordinator: Zanni, Markella V.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.