Effects of night shift work on bone health
Fractured Schedules: Skeletal Effects of Acute and Chronic Night Shift Work
This study looks at how working night shifts might affect bone health in adults, focusing on how changes in sleep patterns can impact bone strength and the risk of fractures, so we can find ways to help those who work these hours stay healthier.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-10897309 on NIH RePORTER |
What this research studies
This research investigates how working night shifts impacts bone metabolism and density in adults. It examines both acute and chronic effects of disrupted sleep patterns and circadian rhythms on bone health, using simulated night shift schedules and real-world data. The study aims to understand the underlying mechanisms that lead to changes in bone formation and resorption, which could increase the risk of fractures. By identifying these effects, the research seeks to provide insights into potential interventions for those affected by night shift work.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who regularly work night shifts and may be experiencing disruptions in their sleep patterns.
Not a fit: Patients who do not work night shifts or have pre-existing severe bone health issues may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for protecting bone health in individuals who work night shifts.
How similar studies have performed: Previous studies have indicated potential risks associated with night shift work, but this specific investigation into bone health is relatively novel.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Swanson, Christine M — University of Colorado Denver
- Study coordinator: Swanson, Christine M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.