NIH-funded research Career grant

Effects of MitoQ on mobility and cognitive performance in older adults

Official title: The Mito-Frail Trial: Effects of MitoQ on Vasodilation, Mobility and Cognitive Performance in Frail Older Adults

Funded at University of Connecticut Storrs · NIH-11035191 · Data updated 2026-11-12

This study is looking at how a supplement called MitoQ might help improve blood flow, movement, and memory in older adults who are feeling frail, with the hope of making life a little easier and better for them.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs
NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project startMarch 15, 2023
Project endFebruary 29, 2028
Funding year2025
Award (this year)$134,535
NIH project number5K01AG080164-03
Project IDNIH-11035191 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are frail older adults who experience difficulties with mobility and cognitive performance.

Less likely to help

Patients who are not frail or do not have age-related mobility or cognitive issues may not benefit from this research.

What this research studies

This research investigates how MitoQ, an antioxidant, affects blood flow, physical mobility, and cognitive abilities in frail older adults. The study aims to understand the potential benefits of MitoQ in improving the quality of life for seniors who may struggle with mobility and memory issues. Participants will be monitored for changes in their physical and mental performance, providing valuable insights into aging and health. The research is part of a broader effort to develop effective interventions for age-related decline.

Why it matters

Potential benefit: If successful, this research could lead to improved mobility and cognitive function in frail older adults, enhancing their independence and quality of life.

How similar studies have gone: Previous research has shown promise in using antioxidants to improve health outcomes in aging populations, suggesting potential success for this approach.

Where this research is happening

  • University of Connecticut Storrs
    Storrs-Mansfield, United States
    Active

Researchers

  • Principal investigator: Kwon, Oh Sung — University of Connecticut Storrs
  • Study coordinator: Kwon, Oh Sung

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.