Effects of light exposure on sleep and inflammation in multiple myeloma patients after stem cell transplantation
Systematic Light Exposure Effects on Circadian Rhythms Entrainment, Inflammation, Neutropenic Fever and Symptom Burden among Multiple Myeloma Patients undergoing Autologous Stem Cell Transplantation
['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-10876916
This study is looking at whether getting morning light can help improve sleep, reduce inflammation, and lower the chances of fever in patients with multiple myeloma who are getting stem cell transplants, so they can feel better during their treatment.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10876916 on ClinicalTrials.gov |
What this research studies
This research investigates how systematic exposure to light can help regulate circadian rhythms in patients with multiple myeloma who are undergoing autologous stem cell transplantation. The study aims to determine if morning light exposure can improve sleep quality, reduce inflammation, and lower the incidence of neutropenic fever, which are common issues faced by these patients. By measuring hormone levels and symptom burden, the research seeks to establish a link between light exposure and better health outcomes. Patients will be randomly assigned to receive either light therapy or standard care to assess the effectiveness of this approach.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults diagnosed with multiple myeloma who are scheduled to undergo autologous stem cell transplantation.
Not a fit: Patients who are not undergoing autologous stem cell transplantation or those with other significant health conditions may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved sleep, reduced inflammation, and better overall health outcomes for multiple myeloma patients undergoing treatment.
How similar studies have performed: Previous studies have shown promising results with light exposure improving sleep and reducing inflammation, indicating that this approach may be effective.
Where this research is happening
NEW YORK, UNITED STATES
- ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: VALDIMARSDOTTIR, HEIDDIS — ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI
- Study coordinator: VALDIMARSDOTTIR, HEIDDIS
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.