Effects of kratom exposure during pregnancy

Kratom alkaloid exposure during pregnancy

['FUNDING_R21'] · UNIVERSITY OF FLORIDA · NIH-10800668

This study is looking at how kratom, a plant some pregnant women might use instead of opioids, affects babies during pregnancy, to help provide better advice for moms-to-be about its safety.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF FLORIDA (nih funded)
Locations1 site (GAINESVILLE, UNITED STATES)
Trial IDNIH-10800668 on ClinicalTrials.gov

What this research studies

This research investigates the impact of kratom, a plant native to Southeast Asia, on fetal development when consumed by pregnant women. It aims to determine whether kratom alkaloids can cross the placental barrier and potentially cause withdrawal symptoms in newborns. The study will analyze various forms of kratom, including its traditional preparation and commercially available products, to assess their effects on both mothers and infants. By understanding these effects, the research seeks to provide clearer guidance for pregnant women who may be using kratom as an alternative to traditional opioids.

Who could benefit from this research

Good fit: Ideal candidates for this research include pregnant women who are currently using kratom or have a history of opioid use.

Not a fit: Patients who are not pregnant or who do not use kratom may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide critical insights into the safety of kratom use during pregnancy, potentially guiding better health decisions for expectant mothers and their babies.

How similar studies have performed: While there is limited research specifically on kratom's effects during pregnancy, studies on other substances have shown that understanding their impact on fetal development can lead to significant advancements in maternal and child health.

Where this research is happening

GAINESVILLE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.