Effects of iron supplements on gut health in preterm infants
Enteral Iron Supplementation and Intestinal Health in Preterm Infants
This study is looking at how different amounts of iron given to preterm babies might affect their gut health, to see if giving too much iron could cause problems with their gut bacteria and inflammation while still helping to prevent anemia.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of South Florida NIH-funded |
| Lab location | 1 site (Tampa, United States) |
| Project ID | NIH-10903925 on NIH RePORTER |
What this research studies
This research investigates how different doses of enteral iron supplementation affect the intestinal health of preterm infants. It aims to determine whether high doses of iron, which are often given to prevent anemia, may lead to harmful changes in gut bacteria and inflammation. By comparing the gut health of infants receiving low versus high iron doses, the study seeks to understand the balance between preventing iron deficiency and maintaining a healthy gut environment. The research combines clinical observations with laboratory studies to provide a comprehensive view of the issue.
Who could benefit from this research
Good fit: Ideal candidates for this research are preterm infants who are at risk for iron deficiency and are receiving enteral iron supplementation.
Not a fit: Patients who are not preterm or those who do not require iron supplementation may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved guidelines for iron supplementation in preterm infants, enhancing their overall health and reducing the risk of intestinal diseases.
How similar studies have performed: Previous research has indicated that iron supplementation can impact gut health, but this specific approach of comparing different dosing regimens in preterm infants is relatively novel.
Where this research is happening
Tampa, United States
- University of South Florida — Tampa, United States (Active)
Researchers
- Principal investigator: Ho, Thao — University of South Florida
- Study coordinator: Ho, Thao
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.