Effects of inhaling engineered nano-materials during pregnancy on health outcomes across generations
Multi-generational Effects of Maternal Engineered Nano-Material Inhalation Exposure on Microvascular and Reproductive Health Outcomes
This study looks at how breathing in tiny engineered materials while pregnant might impact the health of both moms and their babies, focusing on their blood vessels and reproductive health, to help ensure healthier outcomes for both.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | West Virginia University NIH-funded |
| Lab location | 1 site (Morgantown, United States) |
| Project ID | NIH-10831078 on NIH RePORTER |
What this research studies
This research investigates how inhaling engineered nano-materials during pregnancy affects both the mother and her offspring's microvascular and reproductive health. The study uses an inhalation exposure model relevant to occupational settings and examines the epigenetic changes in the offspring. By understanding the hormonal and vascular adaptations that occur during gestation, the research aims to identify critical factors that influence healthy reproductive outcomes. This knowledge is essential for improving maternal and fetal health.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals who may be exposed to engineered nano-materials in their occupational environments.
Not a fit: Patients who are not pregnant or those not exposed to engineered nano-materials may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved health outcomes for mothers and their children by identifying harmful exposures and informing safer practices.
How similar studies have performed: While the specific approach of this research may be novel, there is existing literature on the effects of environmental exposures during pregnancy that supports the relevance of this investigation.
Where this research is happening
Morgantown, United States
- West Virginia University — Morgantown, United States (Active)
Researchers
- Principal investigator: Bowdridge, Elizabeth Compton — West Virginia University
- Study coordinator: Bowdridge, Elizabeth Compton
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.