Effects of influenza on the gut microbiome during pregnancy
Official title: Microbiome-induced changes following influenza infection during pregnancy
Funded at Johns Hopkins University · NIH-11070667 · Data updated 2026-11-12
This study looks at how getting the flu during pregnancy might change the good bacteria in a mom's gut and how that could affect her baby's growth and health.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project start | December 1, 2024 |
| Project end | November 30, 2027 |
| Funding year | 2025 |
| Award (this year) | $76,000 |
| NIH project number | 1F32HD117584-01 |
| Project ID | NIH-11070667 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are pregnant individuals who are at risk of influenza infection and its associated complications.
✕Less likely to help
Patients who are not pregnant or those who do not have a risk of influenza infection may not benefit from this research.
What this research studies
This research investigates how influenza A virus infection during pregnancy affects the maternal gut microbiome and the subsequent impact on fetal development. Using a mouse model, the study aims to understand the changes in microbial diversity and composition caused by the virus, which may lead to adverse outcomes such as intrauterine growth restriction. The research will explore the mechanisms behind these changes and their implications for both maternal and fetal health.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of influenza-related complications during pregnancy, potentially enhancing fetal health outcomes.
How similar studies have gone: Previous research has shown that changes in the gut microbiome can significantly impact health outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
-
Johns Hopkins University
Baltimore, United States Active
Researchers
- Principal investigator: Seibert, Brittany Anne — Johns Hopkins University
- Study coordinator: Seibert, Brittany Anne
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.