Effects of hormone therapy on the rectal mucosa in transgender women
Understanding the rectal mucosal effects of cross-sex hormone therapy among US and Thai transgender women
This study looks at how hormone therapy affects the rectal tissue in transgender women, especially those at risk for HIV, to better understand their health needs and improve HIV prevention strategies just for them.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10672350 on NIH RePORTER |
What this research studies
This research investigates how cross-sex hormone therapy affects the rectal mucosa in transgender women, particularly those at risk for HIV. By examining the biological responses of the rectal tissue to hormone therapy, the study aims to understand how these changes may influence HIV transmission. The research involves collecting biopsies and analyzing the tissue for hormonal effects, which could provide insights into the unique health needs of transgender women. The findings could help tailor HIV prevention strategies specifically for this population.
Who could benefit from this research
Good fit: Ideal candidates for this research are transgender women who are undergoing cross-sex hormone therapy and are at risk for HIV.
Not a fit: Patients who are not transgender women or those not undergoing hormone therapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved HIV prevention strategies tailored for transgender women.
How similar studies have performed: While there has been some research on hormone effects in other areas, this specific investigation into the rectal mucosa of transgender women is novel and has not been extensively studied.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Kelley, Colleen F — Emory University
- Study coordinator: Kelley, Colleen F
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.