Effects of HIV exposure on brain development in children

Long-term neurocognitive outcomes of HIV-exposed uninfected children

['FUNDING_OTHER'] · UNIVERSITY OF MARYLAND BALTIMORE · NIH-11011975

This study looks at how being exposed to HIV before birth affects the brain development of children who are not infected, and it follows moms and their kids over five years to see how different treatments and other factors might influence the kids' growth and learning.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF MARYLAND BALTIMORE (nih funded)
Locations1 site (BALTIMORE, UNITED STATES)
Trial IDNIH-11011975 on ClinicalTrials.gov

What this research studies

This research investigates the long-term neurocognitive outcomes of children who were exposed to HIV in utero but are uninfected themselves. The study follows a cohort of mothers and their infants over a five-year period, assessing various factors that may influence child development, including biological and psychosocial elements. By comparing children born to HIV-positive mothers with different treatment histories, the research aims to understand how these factors affect neurocognitive growth in early childhood.

Who could benefit from this research

Good fit: Ideal candidates for this research are children aged 0-5 years who were exposed to HIV during pregnancy but are not infected themselves.

Not a fit: Patients who are HIV-positive or those who do not fall within the specified age range may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for the neurodevelopmental needs of HIV-exposed uninfected children.

How similar studies have performed: Previous research has shown promising results in understanding the impacts of HIV exposure on child development, making this study a continuation of important work in this area.

Where this research is happening

BALTIMORE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Acquired Immune Deficiency Syndrome Virus, Acquired Immunodeficiency Syndrome Virus

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.