Effects of FGF-21 on fat and liver health in people living with HIV
Metabolic impact of FGF-21 in adipose tissue and liver of PLWH
This study is looking at how a protein called FGF-21 impacts fat and liver health in people with HIV, hoping to find new ways to help manage the weight and liver problems that can come with the condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Texas Hlth Sci Ctr Houston NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-10873755 on NIH RePORTER |
What this research studies
This research investigates how the protein FGF-21 affects fat tissue and liver function in individuals living with HIV. It aims to understand the complex metabolic issues caused by HIV and its treatment, particularly focusing on fat accumulation and liver disease. By studying mouse models, the researchers will explore the relationship between HIV proteins and metabolic changes, with the goal of identifying potential new treatments for these conditions. Patients may benefit from insights that could lead to improved management of metabolic disorders associated with HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who are experiencing metabolic issues such as fat accumulation or liver disease.
Not a fit: Patients who are not living with HIV or do not have metabolic complications related to HIV may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatment strategies for metabolic disorders in people living with HIV.
How similar studies have performed: Previous research has shown promising results in understanding metabolic disorders related to HIV, but this specific approach is novel and aims to uncover new mechanisms.
Where this research is happening
Houston, United States
- University of Texas Hlth Sci Ctr Houston — Houston, United States (Active)
Researchers
- Principal investigator: Lake, Jordan E — University of Texas Hlth Sci Ctr Houston
- Study coordinator: Lake, Jordan E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.