NIH-funded research NIH-funded research

Effects of early-life antipsychotic treatment on brain development

Official title: Brain Development after Early-Life Antipsychotic Treatment

Funded at Northern Kentucky University · NIH-11060960 · Data updated 2026-11-12

This study looks at how taking antipsychotic medications early in life might impact brain development and behavior as kids grow up, especially for those treated for mental health issues, and it also gives college students a chance to learn through hands-on research.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthern Kentucky University
NIH-funded
Lab location1 site (Highland Heights, United States)
Project startJune 1, 2023
Project endApril 30, 2027
Funding year2025
Award (this year)$137,000
NIH project number5R16GM149498-03
Project IDNIH-11060960 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children who have been prescribed antipsychotic medications for psychiatric conditions.

Less likely to help

Patients who have not been treated with antipsychotic medications or those with unrelated psychiatric conditions may not benefit from this research.

What this research studies

This research investigates how early exposure to antipsychotic medications affects brain development and behavior later in life. The study focuses on children who have been treated with these medications for psychiatric disorders and aims to understand the long-term consequences of such treatments. By using animal models, the researchers will examine changes in brain function and responses to drugs of abuse, providing insights into potential risks associated with early antipsychotic use. The research also emphasizes involving undergraduate students in the scientific process, enhancing their educational experience.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and guidelines for the safe use of antipsychotic medications in children.

How similar studies have gone: Previous research has indicated that early exposure to antipsychotic drugs can lead to significant behavioral changes, suggesting that this area of investigation is both relevant and necessary.

Where this research is happening

  • Northern Kentucky University
    Highland Heights, United States
    Active

Researchers

  • Principal investigator: Bardgett, Mark Edward — Northern Kentucky University
  • Study coordinator: Bardgett, Mark Edward

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.