Effects of e-cigarettes on pregnancy and reproductive health

Investigating Implications of E-Cigarettes on Pregnancy Success and Reproductive Fitness

['FUNDING_OTHER'] · DUKE UNIVERSITY · NIH-10892982

This study looks at how using e-cigarettes might affect pregnancy and the health of unborn babies, especially focusing on how they could interfere with the early stages of pregnancy for women who are pregnant or trying to conceive.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorDUKE UNIVERSITY (nih funded)
Locations1 site (DURHAM, UNITED STATES)
Trial IDNIH-10892982 on ClinicalTrials.gov

What this research studies

This research investigates how the use of e-cigarettes, particularly among pregnant women, affects pregnancy success and reproductive health. It focuses on the biological processes involved in embryo implantation and the potential toxic effects of e-cigarette ingredients on these processes. By examining the molecular and hormonal signaling events during early pregnancy, the study aims to uncover the mechanisms by which e-cigarettes may delay implantation and impact fetal development. The research employs a combination of transcriptomic analysis and biological assessments to evaluate the effects of e-cigarette exposure.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant women or those planning to become pregnant who use e-cigarettes.

Not a fit: Patients who do not use e-cigarettes or are not pregnant may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide critical insights into the safety of e-cigarette use during pregnancy, potentially leading to better health outcomes for mothers and their babies.

How similar studies have performed: While there is limited research specifically on e-cigarettes and pregnancy, studies on smoking and pregnancy outcomes have shown significant risks, suggesting that this area of investigation is both relevant and necessary.

Where this research is happening

DURHAM, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.