Effects of e-cigarette use on heart and lung health over time
Official title: Longitudinal Effects of E-cigarette Use on Cardiovascular and Pulmonary Health
Funded at University of Wisconsin-Madison · NIH-10943297 · Data updated 2026-11-12
This study is looking at how using e-cigarettes for a long time affects heart and lung health, and it's for people who have been using e-cigarettes regularly, as well as some who don’t use any tobacco products at all.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project start | September 6, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $1,257,395 |
| NIH project number | 1R01HL175602-01 |
| Project ID | NIH-10943297 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are long-term users of e-cigarettes who are stable in their usage patterns.
✕Less likely to help
Patients who do not use e-cigarettes or combustible cigarettes will not benefit from this research.
What this research studies
This research investigates the long-term health effects of electronic nicotine delivery systems (ENDS), commonly known as e-cigarettes, on cardiovascular and pulmonary health. It aims to understand how factors such as the amount of e-cigarette use, age, body weight, and the use of other tobacco products influence health outcomes. The study will involve 400 long-term e-cigarette users and 200 control participants who do not use e-cigarettes or combustible cigarettes, with comprehensive health assessments conducted over 36 months. These assessments will include various biomarkers related to heart and lung health, as well as measurements of arterial structure and nervous system activity.
Why it matters
Potential benefit: If successful, this research could provide valuable insights into the health risks associated with long-term e-cigarette use, potentially guiding public health recommendations and individual choices.
How similar studies have gone: While there is ongoing research into the effects of e-cigarettes, this study aims to provide novel insights into their long-term health impacts, making it a significant addition to the existing body of knowledge.
Where this research is happening
-
University of Wisconsin-Madison
Madison, United States Active
Researchers
- Principal investigator: Baker, Timothy B — University of Wisconsin-Madison
- Study coordinator: Baker, Timothy B
Related research
Other NIH-funded projects on the same topics.
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A long-term study will follow people who vape and non-vapers to see how vaping might influence heart and lung health over three years.
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How social media and cultural background shape e-cigarette use in Mexican American college students
This project looks at whether exposure to e-cigarette content on platforms like TikTok and YouTube and a student's cultural background relate to vaping among Mexican American college students.
-
E-cigarette use and emphysema risk in young adults (VapeScan)
A study to understand whether vaping or traditional cigarettes cause early lung damage in young adults.
-
How vaping affects teens' brains and thinking
This project looks at whether using e-cigarettes (vaping) changes brain development and thinking skills in children and teenagers.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.