Effects of Dolutegravir on HIV treatment outcomes and health risks in South Africa.

Impact of Dolutegravir on Viral Suppression, Retention, and Risk of Non-Communicable Diseases among Persons Living with HIV in South Africa.

NIH-funded research Boston University Medical Campus · NIH-10932563

This study is looking at how the HIV medication dolutegravir helps people in South Africa stay healthy and manage their condition, especially in terms of keeping the virus under control and staying in regular care, while also checking for any long-term health issues that might come up.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionBoston University Medical Campus NIH-funded
Lab location1 site (Boston, United States)
Project IDNIH-10932563 on NIH RePORTER

What this research studies

This research investigates how the antiretroviral drug dolutegravir affects the health outcomes of individuals living with HIV in South Africa, particularly focusing on viral suppression and retention in care. It aims to understand the long-term implications of dolutegravir treatment, especially concerning the risk of developing non-communicable diseases. By analyzing data from patients who have started treatment with dolutegravir, the study seeks to provide insights into the effectiveness of this medication compared to previous treatments. The research will utilize advanced epidemiological methods to assess these outcomes over time.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals living with HIV in South Africa who are receiving or have received treatment with dolutegravir.

Not a fit: Patients who are not living with HIV or those who are not on a dolutegravir-based treatment regimen may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for HIV patients, enhancing their overall health and reducing the risk of additional diseases.

How similar studies have performed: Previous research has shown promising results regarding the effectiveness of dolutegravir, but this specific investigation into its long-term health impacts is novel.

Where this research is happening

Boston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome VirusAdult-Onset Diabetes Mellitus
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.