Effects of diet and exercise on cognitive health in older adults
Age-related Cognitive Changes: Effects of Combined Flavonoid Intake and Physical Exertion Mediated by the Gut Microbiome
['FUNDING_R01'] · NORTH CAROLINA STATE UNIVERSITY RALEIGH · NIH-11176254
This study is looking at how eating foods high in flavonoids and staying active can help improve brain health in older adults over 65, while also checking how our gut health plays a role in this process.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | NORTH CAROLINA STATE UNIVERSITY RALEIGH (nih funded) |
| Locations | 1 site (RALEIGH, UNITED STATES) |
| Trial ID | NIH-11176254 on ClinicalTrials.gov |
What this research studies
This research investigates how a diet rich in flavonoids combined with regular physical activity can influence cognitive changes in older adults, particularly those over 65. It focuses on the role of the gut microbiome in mediating these effects, as previous studies suggest that both diet and exercise can enhance cognitive performance and reduce the risk of dementia. Participants may engage in dietary modifications and exercise routines while researchers monitor changes in cognitive function and gut health. The study aims to establish a clear link between these lifestyle factors and cognitive health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults aged 65 and older who are interested in improving their cognitive health through diet and exercise.
Not a fit: Patients who are not 65 years or older or those with severe cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to effective dietary and exercise recommendations that help maintain cognitive function and reduce the risk of dementia in older adults.
How similar studies have performed: Previous research has shown promising results in the cognitive benefits of flavonoid-rich diets and physical activity, suggesting that this approach may be effective.
Where this research is happening
RALEIGH, UNITED STATES
- NORTH CAROLINA STATE UNIVERSITY RALEIGH — RALEIGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LILA, MARY ANN ANN — NORTH CAROLINA STATE UNIVERSITY RALEIGH
- Study coordinator: LILA, MARY ANN ANN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.