Effects of diabetes medications during pregnancy on mothers and children

Comparing the effects of pharmacological treatment for gestational diabetes on long-term maternal and child health outcomes

NIH-funded research Kaiser Foundation Research Institute · NIH-11002709

This study looks at how different medications for gestational diabetes, like metformin, glyburide, and insulin, impact the long-term health of moms and their kids, helping to find the best treatment options for a healthier future.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project IDNIH-11002709 on NIH RePORTER

What this research studies

This research investigates how different medications used to treat gestational diabetes affect the long-term health of mothers and their children. By analyzing data from over 44,000 patients at Kaiser Permanente, the study will track health outcomes for up to 18 years after treatment. It focuses on those who required medication during pregnancy and compares the effects of metformin, glyburide, and insulin. The goal is to understand the best treatment options for improving health outcomes for both mothers and their children.

Who could benefit from this research

Good fit: Ideal candidates for this research are pregnant individuals diagnosed with gestational diabetes who required pharmacological treatment.

Not a fit: Patients who do not have gestational diabetes or those who managed their condition solely through diet will not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies for gestational diabetes, enhancing the long-term health of mothers and their children.

How similar studies have performed: Previous research has shown that pharmacological treatments can have significant effects on health outcomes, but this specific approach to comparing long-term effects is novel.

Where this research is happening

Oakland, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.