Effects of chronic THC exposure during adolescence on brain and behavior
Neural and Behavioral Consequences of Chronic THC Exposure During Adolescence
This study looks at how using cannabis often during teenage years affects the brains and thinking skills of young squirrel monkeys, helping us understand the potential long-term risks for teens who use cannabis.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mclean Hospital NIH-funded |
| Lab location | 1 site (Belmont, United States) |
| Project ID | NIH-11046405 on NIH RePORTER |
What this research studies
This research investigates how frequent cannabis use during adolescence affects brain structure and function, as well as cognitive and motivational processes. By studying both male and female squirrel monkeys, the researchers aim to understand the long-term impacts of THC exposure during this critical developmental period. The study employs neuroimaging and behavioral assessments to evaluate changes in brain connectivity and cognitive abilities that may persist into adulthood. The findings could provide insights into the health risks associated with adolescent cannabis use.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12-20 who have a history of cannabis use.
Not a fit: Patients who have not used cannabis or are outside the adolescent age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could help identify long-term health risks associated with adolescent cannabis use, informing prevention and treatment strategies.
How similar studies have performed: Previous studies have shown that adolescent cannabis exposure can lead to significant changes in brain function and behavior, suggesting that this research builds on established findings.
Where this research is happening
Belmont, United States
- Mclean Hospital — Belmont, United States (Active)
Researchers
- Principal investigator: Bergman, Jack — Mclean Hospital
- Study coordinator: Bergman, Jack
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.