Effects of chemical exposures on brain function and behavior in adolescents
Brain Influences of Phthalates and Bisphenols in Adolescents
This study is looking at how being exposed to certain chemicals during important growth stages might affect thinking and behavior in teenagers, and it's for parents and caregivers who want to understand how these substances could impact their kids as they grow up.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-10877052 on NIH RePORTER |
What this research studies
This research investigates how exposure to phthalates and bisphenols during critical developmental periods affects executive function and behavior in adolescents. By analyzing data from a large Dutch birth cohort, the study will measure urinary levels of these chemicals in participants at ages 9-10 and 13-14, and evaluate their cognitive and behavioral outcomes at ages 16-18. The research aims to understand the neurotoxic effects of these exposures and the underlying mechanisms involved, utilizing advanced neuroimaging techniques.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents aged 12-20 who have been exposed to phthalates and bisphenols during prenatal and early childhood periods.
Not a fit: Patients who are not within the age range of 0-20 years or who have not been exposed to the chemicals of interest may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of how environmental chemicals impact adolescent brain development and behavior, potentially informing public health policies.
How similar studies have performed: Previous research has shown significant negative impacts of prenatal exposure to phthalates and bisphenols on cognitive and behavioral outcomes, indicating that this approach has a foundation in established findings.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Ghassabian, Akhgar — New York University School of Medicine
- Study coordinator: Ghassabian, Akhgar
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.