Effects of cannabis on brain development and function throughout life
Impact of Cannabinoid Across the Lifespan (ICAL)
This study looks at how using cannabis during teenage years can affect brain development and function later in life, helping us understand the potential risks for young people who use it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-11120987 on NIH RePORTER |
What this research studies
This research investigates how cannabis use, particularly during adolescence, affects brain development and function across the lifespan. It focuses on understanding the impact of Δ9-tetrahydrocannabinol (THC) on the endocannabinoid system and how early exposure may lead to long-term cognitive and emotional impairments. The study employs a combination of molecular, synaptic, and behavioral approaches, using animal models to simulate adolescent cannabis consumption patterns and assess the resulting neurobehavioral changes. By examining these effects, the research aims to provide insights into the risks associated with adolescent cannabis use.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents and young adults who have used cannabis or are at risk of using it.
Not a fit: Patients who have not used cannabis or are not in the adolescent to young adult age range may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and prevention of cognitive and emotional impairments linked to adolescent cannabis use.
How similar studies have performed: Previous research has indicated that adolescent cannabis use can lead to lasting cognitive and emotional effects, supporting the relevance of this investigation.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Piomelli, Daniele — University of California-Irvine
- Study coordinator: Piomelli, Daniele
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.