Effects of cannabis on brain development and behavior

Molecular underpinnings of the developmental Effects of Cannabis

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11093522

This study looks at how using cannabis during pregnancy might affect the brain development and behavior of children and teenagers, focusing on the effects of THC, the active ingredient in cannabis, to better understand any long-term impacts on mental health and decision-making.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11093522 on ClinicalTrials.gov

What this research studies

This research investigates how cannabis use, particularly during pregnancy, affects brain development and behavior in children and adolescents. It focuses on the impact of THC, the main psychoactive component of cannabis, on neurodevelopmental processes and immune system changes. By analyzing gene expression and behavioral outcomes, the study aims to uncover the long-term effects of prenatal cannabis exposure on mental health and decision-making. The research employs both human and animal models to explore these complex interactions.

Who could benefit from this research

Good fit: Ideal candidates for this research include pregnant women who use cannabis and their children, as well as adolescents exposed to cannabis during development.

Not a fit: Patients who have not been exposed to cannabis during pregnancy or early development may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention strategies for the negative effects of cannabis on developing brains.

How similar studies have performed: Previous research has shown significant effects of prenatal cannabis exposure on child development, indicating that this area of study is both relevant and critical.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: addictive disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.