Effects of cannabinoids on brain development during adolescence

Impact of Cannabinoid Across the Lifespan (ICAL)

NIH-funded research University of California-Irvine · NIH-11121007

This study looks at how using THC, a part of cannabis, during teenage years can change brain development and behavior, helping us understand any lasting effects it might have on thinking and actions.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California-Irvine NIH-funded
Lab location1 site (Irvine, United States)
Project IDNIH-11121007 on NIH RePORTER

What this research studies

This research investigates how exposure to THC, a component of cannabis, during adolescence affects brain development and behavior. It focuses on understanding the genetic and epigenetic changes that occur in the endocannabinoid system due to this exposure. The study aims to identify persistent cognitive and behavioral abnormalities that may arise from these changes. By fostering innovative research and providing mentorship, the project also supports the development of new researchers in the field of cannabinoid studies.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents aged 12 to 20 who have been exposed to THC or are at risk of cannabis use.

Not a fit: Patients outside the age range of 12 to 20 or those who have not been exposed to THC may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and prevention of cognitive and behavioral issues related to adolescent cannabis use.

How similar studies have performed: Previous research has shown significant effects of THC exposure on brain development, indicating that this approach is grounded in established findings.

Where this research is happening

Irvine, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions addictive disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.