Effects of cannabinoids on brain development during adolescence

Impact of Cannabinoid Across the Lifespan (ICAL)

['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10932779

This study is looking at how using THC, a part of cannabis, during teenage years can change the way the brain develops and works, and it’s for anyone interested in understanding the long-term effects of cannabis on young people's thinking and behavior.

Quick facts

Phase['FUNDING_OTHER']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA-IRVINE (nih funded)
Locations1 site (IRVINE, UNITED STATES)
Trial IDNIH-10932779 on ClinicalTrials.gov

What this research studies

This research investigates how exposure to THC, a component of cannabis, during adolescence affects the brain's development and function. It focuses on understanding the genetic and epigenetic changes that occur in the endocannabinoid system due to this exposure. The study aims to identify persistent cognitive and behavioral changes that may result from these alterations. By fostering innovative research and supporting new investigators, the project seeks to advance knowledge in cannabinoid effects across different life stages.

Who could benefit from this research

Good fit: Ideal candidates for participation are adolescents aged 12 to 20 who may be exposed to THC.

Not a fit: Patients outside the age range of 12 to 20 or those who have not been exposed to THC may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of the impacts of cannabis use on adolescent brain development.

How similar studies have performed: Previous research has shown significant effects of THC exposure on brain development, indicating that this area of study is both relevant and critical.

Where this research is happening

IRVINE, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.