Effects of cannabinoids on brain development and memory in adolescents and adults
Impact of Cannabinoid Across the Lifespan (ICAL)
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-10932781
This study looks at how using cannabis as a teenager might change brain development, especially in areas related to memory and learning, and it aims to help us understand how these effects can vary based on age and gender.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-10932781 on ClinicalTrials.gov |
What this research studies
This research investigates how cannabis use during adolescence affects brain development, particularly focusing on memory and learning. It examines the neurobiological mechanisms behind these effects, including how cannabinoids influence synaptic plasticity in the brain. The study aims to understand the differences in these effects based on age and sex, using both animal models and human data to draw conclusions. By exploring these relationships, the research seeks to provide insights into the long-term impacts of cannabis on cognitive functions.
Who could benefit from this research
Good fit: Ideal candidates for participation include adolescents aged 12-20 who have used cannabis and adults over 21 who may have experienced cognitive changes related to cannabis use.
Not a fit: Patients who have never used cannabis or those with pre-existing severe cognitive impairments unrelated to cannabis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of cognitive impairments associated with cannabis use in young people.
How similar studies have performed: Previous research has indicated significant effects of cannabinoids on cognitive functions, suggesting that this study builds on established findings rather than exploring entirely novel territory.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: GALL, CHRISTINE M — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: GALL, CHRISTINE M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.