Effects of cannabidiol on HIV and methamphetamine-related brain inflammation
Official title: Impact of cannabidiol on HIV infection and methamphetamine abuse associated neuroinflammation
Funded at University of Nebraska Medical Center · NIH-11061421 · Data updated 2026-11-12
This study is looking at whether CBD, a natural compound from cannabis, can help reduce brain inflammation in people living with HIV who also use methamphetamine, with the goal of improving their health and quality of life.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project start | April 1, 2024 |
| Project end | March 31, 2026 |
| Funding year | 2025 |
| Award (this year) | $153,500 |
| NIH project number | 5R03DA060076-02 |
| Project ID | NIH-11061421 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals living with HIV who also have a history of methamphetamine abuse.
✕Less likely to help
Patients who do not have HIV or a history of methamphetamine abuse may not benefit from this research.
What this research studies
This research investigates how cannabidiol (CBD), a compound found in cannabis, may help reduce neuroinflammation in individuals living with HIV who also abuse methamphetamine. The study aims to understand the relationship between HIV, methamphetamine use, and inflammation in the brain, which can lead to cognitive disorders. By examining the potential of CBD to mitigate these inflammatory responses, the research seeks to develop effective strategies to improve the health and quality of life for people affected by both HIV and substance abuse.
Why it matters
Potential benefit: If successful, this research could provide new therapeutic options for individuals living with HIV and struggling with methamphetamine addiction, potentially improving their neurological health.
How similar studies have gone: Previous studies have shown that CBD can reduce inflammation, suggesting that this approach may hold promise, although the specific combination of HIV and methamphetamine-related neuroinflammation is less explored.
Where this research is happening
-
University of Nebraska Medical Center
Omaha, United States Active
Researchers
- Principal investigator: Chand, Subhash — University of Nebraska Medical Center
- Study coordinator: Chand, Subhash
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.