Effects of cannabidiol on HIV and methamphetamine-related brain inflammation
Impact of cannabidiol on HIV infection and methamphetamine abuse associated neuroinflammation
This study is looking at whether CBD, a natural compound from cannabis, can help reduce brain inflammation in people living with HIV who also use methamphetamine, with the goal of improving their health and quality of life.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Nebraska Medical Center NIH-funded |
| Lab location | 1 site (Omaha, United States) |
| Project ID | NIH-11061421 on NIH RePORTER |
What this research studies
This research investigates how cannabidiol (CBD), a compound found in cannabis, may help reduce neuroinflammation in individuals living with HIV who also abuse methamphetamine. The study aims to understand the relationship between HIV, methamphetamine use, and inflammation in the brain, which can lead to cognitive disorders. By examining the potential of CBD to mitigate these inflammatory responses, the research seeks to develop effective strategies to improve the health and quality of life for people affected by both HIV and substance abuse.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals living with HIV who also have a history of methamphetamine abuse.
Not a fit: Patients who do not have HIV or a history of methamphetamine abuse may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could provide new therapeutic options for individuals living with HIV and struggling with methamphetamine addiction, potentially improving their neurological health.
How similar studies have performed: Previous studies have shown that CBD can reduce inflammation, suggesting that this approach may hold promise, although the specific combination of HIV and methamphetamine-related neuroinflammation is less explored.
Where this research is happening
Omaha, United States
- University of Nebraska Medical Center — Omaha, United States (Active)
Researchers
- Principal investigator: Chand, Subhash — University of Nebraska Medical Center
- Study coordinator: Chand, Subhash
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.