Effects of cannabidiol on cognitive health in older adults with HIV

Neurocognitive implications of cannabidiol (CBD) while aging with HIV

NIH-funded research Florida International University · NIH-10641920

This study is looking at how CBD might help older adults with HIV by checking if it can improve memory and reduce anxiety, especially as they deal with age-related brain changes and inflammation.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionFlorida International University NIH-funded
Lab location1 site (Miami, United States)
Project IDNIH-10641920 on NIH RePORTER

What this research studies

This research investigates how cannabidiol (CBD) may influence neurocognitive health in older adults living with HIV. It focuses on understanding the potential benefits and risks of CBD use in this population, particularly regarding age-related cognitive decline and inflammation associated with HIV. The study uses a mouse model to explore how CBD affects memory and anxiety in the context of HIV-induced neurocognitive deficits. By examining these effects, the research aims to provide insights that could inform treatment options for aging individuals with HIV.

Who could benefit from this research

Good fit: Ideal candidates for this research are older adults aged 21 and above who are living with HIV and experiencing cognitive challenges.

Not a fit: Patients who are not living with HIV or who are younger than 21 years old may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to new therapeutic strategies for improving cognitive health in older adults living with HIV.

How similar studies have performed: While the specific effects of CBD on aging with HIV are not extensively studied, there is evidence suggesting that cannabinoids may have therapeutic potential in age-related cognitive decline, indicating a promising area of exploration.

Where this research is happening

Miami, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.