Effects of breast cancer treatments on heart health over time
Long Term Effects of Breast Cancer Therapy on Cardiac Remodeling and Function
This study looks at how certain long-term breast cancer treatments might impact heart health over time, helping doctors understand any heart problems that could develop years after treatment, so they can better care for patients like you.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Pennsylvania NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project ID | NIH-10475641 on NIH RePORTER |
What this research studies
This research investigates how long-term breast cancer therapies, particularly anthracyclines and HER2+ targeted treatments, affect heart function and structure in patients. It aims to understand the incidence and severity of cardiac issues that may arise years after treatment, focusing on conditions like cardiomyopathy and heart failure. By utilizing data from a large cohort of breast cancer patients, the study seeks to provide insights into the long-term cardiovascular risks associated with these therapies, which could help in managing patient care post-treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are breast cancer patients who have received anthracycline or HER2+ targeted therapies.
Not a fit: Patients who have not undergone these specific breast cancer treatments may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved monitoring and management strategies for heart health in breast cancer survivors.
How similar studies have performed: Previous research has indicated short-term cardiac risks associated with these therapies, but this study aims to explore long-term effects, making it a novel approach.
Where this research is happening
Philadelphia, United States
- University of Pennsylvania — Philadelphia, United States (Active)
Researchers
- Principal investigator: Ky, Bonnie — University of Pennsylvania
- Study coordinator: Ky, Bonnie
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.