Effects of blood sugar levels on brain health in newborns with brain injury
Neurological Outcome of Glycemia in Neonatal Encephalopathy
This study looks at how high blood sugar levels can impact the brains of newborns with a condition called hypoxic-ischemic encephalopathy (HIE), and it aims to help parents understand how these early sugar levels might affect their child's development as they grow.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Hospital for Sick Chldrn (Toronto) NIH-funded |
| Lab location | 1 site (Toronto, Canada) |
| Project ID | NIH-10844559 on NIH RePORTER |
What this research studies
This research investigates how blood sugar levels, particularly hyperglycemia, affect brain outcomes in newborns suffering from hypoxic-ischemic encephalopathy (HIE). By using continuous glucose monitoring, the study aims to clarify the relationship between elevated glucose levels and brain injury, cognitive function, and behavioral issues in affected infants. The research will assess how these early glucose-related findings translate into long-term developmental outcomes as the children grow. Parents of newborns with HIE may find this study relevant as it seeks to improve understanding and management of their child's condition.
Who could benefit from this research
Good fit: Ideal candidates for this research are newborns diagnosed with hypoxic-ischemic encephalopathy.
Not a fit: Patients who do not have hypoxic-ischemic encephalopathy or are older than newborns may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better management strategies for blood sugar levels in newborns with HIE, potentially improving their long-term neurological outcomes.
How similar studies have performed: Previous studies have indicated that managing glucose levels can significantly impact neurological outcomes, suggesting that this approach may yield valuable insights.
Where this research is happening
Toronto, Canada
- Hospital for Sick Chldrn (Toronto) — Toronto, Canada (Active)
Researchers
- Principal investigator: Tam, Emily Wing Yun — Hospital for Sick Chldrn (Toronto)
- Study coordinator: Tam, Emily Wing Yun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.