Effects of baking soda on heart health in chronic kidney disease
Cardiovascular effects of oral bicarbonate in CKD
This study is looking at how taking bicarbonate can help heart health in people with chronic kidney disease, while also checking for any possible side effects, to find safer ways to manage their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-10911061 on NIH RePORTER |
What this research studies
This research investigates how oral bicarbonate treatment affects cardiovascular health in patients with chronic kidney disease (CKD). It focuses on understanding the balance between the benefits of bicarbonate in preventing metabolic acidosis and its potential risks, such as increased blood pressure and vascular calcification. The study will measure levels of specific hormones and markers related to heart health and fluid balance in CKD patients receiving bicarbonate treatment. By analyzing these effects, the research aims to provide insights into safer treatment options for managing CKD.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic kidney disease who are experiencing metabolic acidosis.
Not a fit: Patients with normal kidney function or those not experiencing metabolic acidosis may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies that minimize cardiovascular risks for patients with chronic kidney disease.
How similar studies have performed: Previous research has indicated potential cardiovascular risks associated with bicarbonate treatment, but this specific investigation into its hormonal effects in CKD is novel.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Raphael, Kalani Lukela — University of Utah
- Study coordinator: Raphael, Kalani Lukela
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.