NIH-funded research R01 grant

Effects of Baduanjin exercise on memory and cognitive decline in older adults

Official title: Modulation effects of Baduanjin mind-body exercise on subjective cognitive decline

Funded at Massachusetts General Hospital · NIH-10688181 · Data updated 2026-11-12

This study is looking at whether practicing Baduanjin, a gentle exercise routine, can help older adults who feel like their memory is slipping but haven't been diagnosed with serious problems, by improving their memory and brain function.

More Cognitive Decline research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMassachusetts General Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 15, 2019
Project endJune 30, 2026
Funding year2023
Award (this year)$806,069
NIH project number5R01AG063975-05
Project IDNIH-10688181 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are older adults who are experiencing subjective cognitive decline but do not yet have a diagnosis of Alzheimer's disease or other significant cognitive impairments.

Less likely to help

Patients who are already diagnosed with advanced Alzheimer's disease or other severe cognitive impairments may not benefit from this research.

What this research studies

This research investigates how Baduanjin, a simple mind-body exercise, can help improve memory and cognitive function in older adults experiencing subjective cognitive decline. The study focuses on older individuals who report memory issues but have not yet developed significant clinical impairment. Participants will engage in Baduanjin exercises, which consist of eight easy movements that can be practiced at home with video guidance. The research aims to determine the effectiveness of this intervention in preventing further cognitive decline and enhancing brain function.

Why it matters

Potential benefit: If successful, this research could provide a non-invasive, accessible method for older adults to improve their cognitive health and potentially delay the onset of Alzheimer's disease.

How similar studies have gone: Previous studies have shown that mind-body interventions like Baduanjin can significantly improve cognitive function in older adults, indicating a promising approach for this research.

Where this research is happening

  • Massachusetts General Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Kong, Jian — Massachusetts General Hospital
  • Study coordinator: Kong, Jian

Related research

Other NIH-funded projects on the same topics.

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  • Understanding early signs of cognitive decline using health records and AI

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  • Creating an online mindfulness program for adults experiencing cognitive decline

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  • Understanding cognitive decline in older Hispanics/Latinos

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  • Investigating how sleep and physical frailty affect cognitive decline in older adults

    This study is looking at how sleep problems and physical weakness in older adults with early signs of memory issues might affect their thinking skills and risk of developing dementia, with the goal of finding ways to help them stay mentally sharp longer.

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.