Effects of androgens on reproductive health in transgender individuals
Official title: Androgen effects on the reproductive neuroendocrine axis
Funded at University of California, San Diego · NIH-11000334 · Data updated 2026-11-12
This study looks at how hormone treatments with androgens might affect the reproductive health of transgender individuals, helping us understand how these hormones can influence fertility and hormone balance in the brain, with the goal of finding better ways to support reproductive health in the LGBTQ+ community.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project start | December 12, 2023 |
| Project end | March 3, 2025 |
| Funding year | 2025 |
| Award (this year) | $193,890 |
| NIH project number | 5R01HD111650-02 |
| Project ID | NIH-11000334 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are transgender individuals undergoing androgen treatment who are concerned about their reproductive health.
✕Less likely to help
Patients who are not undergoing androgen treatment or who do not identify as transgender may not benefit from this research.
What this research studies
This research investigates how androgen treatments affect the reproductive neuroendocrine system in transgender individuals. It aims to understand the mechanisms by which high levels of androgens can disrupt hormone secretion related to reproduction. By studying the impact of androgens on specific brain cells involved in hormone regulation, the research seeks to uncover the effects on fertility and reproductive health. The findings could lead to better interventions for improving reproductive health in sexual and gender minority populations.
Why it matters
Potential benefit: If successful, this research could lead to improved fertility care and reproductive health interventions for transgender individuals.
How similar studies have gone: While there has been some research on androgens and reproductive health, this specific focus on transgender individuals and the neuroendocrine mechanisms involved is relatively novel.
Where this research is happening
-
University of California, San Diego
La Jolla, United States Active
Researchers
- Principal investigator: Kauffman, Alexander S — University of California, San Diego
- Study coordinator: Kauffman, Alexander S
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.