Effects of androgens on reproductive health in transgender individuals

Androgen effects on the reproductive neuroendocrine axis

NIH-funded research University of California, San Diego · NIH-11000334

This study looks at how hormone treatments with androgens might affect the reproductive health of transgender individuals, helping us understand how these hormones can influence fertility and hormone balance in the brain, with the goal of finding better ways to support reproductive health in the LGBTQ+ community.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego NIH-funded
Lab location1 site (La Jolla, United States)
Project IDNIH-11000334 on NIH RePORTER

What this research studies

This research investigates how androgen treatments affect the reproductive neuroendocrine system in transgender individuals. It aims to understand the mechanisms by which high levels of androgens can disrupt hormone secretion related to reproduction. By studying the impact of androgens on specific brain cells involved in hormone regulation, the research seeks to uncover the effects on fertility and reproductive health. The findings could lead to better interventions for improving reproductive health in sexual and gender minority populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are transgender individuals undergoing androgen treatment who are concerned about their reproductive health.

Not a fit: Patients who are not undergoing androgen treatment or who do not identify as transgender may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved fertility care and reproductive health interventions for transgender individuals.

How similar studies have performed: While there has been some research on androgens and reproductive health, this specific focus on transgender individuals and the neuroendocrine mechanisms involved is relatively novel.

Where this research is happening

La Jolla, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.