Effects of alphavirus infection on muscle health
Official title: Acute and chronic effects on skeletal muscle from alphavirus infection
Funded at University of Utah · NIH-11104034 · Data updated 2026-11-12
This study is looking at how infections from Ross River and Chikungunya viruses can harm your muscles and cause issues like pain and weakness, using mice to learn more about what happens in the body so we can find better ways to help people who are affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project start | May 15, 2025 |
| Project end | April 30, 2030 |
| Funding year | 2025 |
| Award (this year) | $640,905 |
| NIH project number | 1R01AR085598-01 |
| Project ID | NIH-11104034 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals who have experienced infections from Ross River or Chikungunya viruses and are suffering from muscle-related symptoms.
✕Less likely to help
Patients who have not been infected with Ross River or Chikungunya viruses are unlikely to benefit from this research.
What this research studies
This research investigates how infections from Ross River and Chikungunya viruses impact skeletal muscle, leading to conditions like myopathy and chronic pain. By using advanced mouse models and genetic techniques, the team aims to understand the mechanisms behind muscle damage and the body's response to these viral infections. The study will explore both the immediate and long-term effects of these viruses on muscle structure and function, providing insights into potential treatments for affected patients.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from chronic muscle pain and dysfunction caused by viral infections.
How similar studies have gone: Other research has shown promising results in understanding viral impacts on muscle health, but this specific approach is relatively novel.
Where this research is happening
-
University of Utah
Salt Lake City, United States Active
Researchers
- Principal investigator: Kardon, Gabrielle — University of Utah
- Study coordinator: Kardon, Gabrielle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.