Effects of alphavirus infection on muscle health
Acute and chronic effects on skeletal muscle from alphavirus infection
This study is looking at how infections from Ross River and Chikungunya viruses can harm your muscles and cause issues like pain and weakness, using mice to learn more about what happens in the body so we can find better ways to help people who are affected.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Utah NIH-funded |
| Lab location | 1 site (Salt Lake City, United States) |
| Project ID | NIH-11104034 on NIH RePORTER |
What this research studies
This research investigates how infections from Ross River and Chikungunya viruses impact skeletal muscle, leading to conditions like myopathy and chronic pain. By using advanced mouse models and genetic techniques, the team aims to understand the mechanisms behind muscle damage and the body's response to these viral infections. The study will explore both the immediate and long-term effects of these viruses on muscle structure and function, providing insights into potential treatments for affected patients.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals who have experienced infections from Ross River or Chikungunya viruses and are suffering from muscle-related symptoms.
Not a fit: Patients who have not been infected with Ross River or Chikungunya viruses are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for patients suffering from chronic muscle pain and dysfunction caused by viral infections.
How similar studies have performed: Other research has shown promising results in understanding viral impacts on muscle health, but this specific approach is relatively novel.
Where this research is happening
Salt Lake City, United States
- University of Utah — Salt Lake City, United States (Active)
Researchers
- Principal investigator: Kardon, Gabrielle — University of Utah
- Study coordinator: Kardon, Gabrielle
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.