Effects of acetaminophen exposure during pregnancy on lung development
Pulmonary implications of perinatal acetaminophen exposure
This study is looking at how taking acetaminophen while pregnant might affect the lung development of babies, helping to understand if it could cause any harm to their breathing health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project ID | NIH-11084412 on NIH RePORTER |
What this research studies
This research investigates how exposure to acetaminophen during pregnancy may affect lung development in newborns. The study focuses on understanding the mechanisms by which acetaminophen, commonly perceived as safe, could potentially harm the developing lungs of infants. Researchers will examine the expression of specific enzymes in lung cells during critical stages of development and assess the impact of acetaminophen on lung injury. By analyzing these effects, the research aims to provide insights into the safety of acetaminophen use during pregnancy and its implications for respiratory health in children.
Who could benefit from this research
Good fit: Ideal candidates for this research include pregnant individuals who have used acetaminophen during their pregnancy or newborns who have been exposed to acetaminophen in neonatal care.
Not a fit: Patients who have not been exposed to acetaminophen during pregnancy or newborns who did not receive acetaminophen treatment are unlikely to benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved guidelines for acetaminophen use during pregnancy, enhancing the respiratory health of newborns.
How similar studies have performed: While the safety of acetaminophen is widely assumed, this research addresses a relatively novel area of inquiry regarding its effects on lung development, indicating that similar studies have not extensively explored this specific aspect.
Where this research is happening
Aurora, UNITED STATES
- University of Colorado Denver — Aurora, United States (Active)
Researchers
- Principal investigator: Wright, Clyde Jason — University of Colorado Denver
- Study coordinator: Wright, Clyde Jason
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.