Effects of 4th-generation e-cigarettes on asthma and inflammation

Immunomodulation and Inflammation Caused by 4th-generation E-cigarettes in the Setting of Asthma

NIH-funded research VA San Diego Healthcare System · NIH-10917660

This study is looking at how using new e-cigarettes might affect inflammation in the lungs of people with asthma, especially veterans and active-duty military members, to help understand the health risks of vaping for those with this condition.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA San Diego Healthcare System NIH-funded
Lab location1 site (San Diego, United States)
Project IDNIH-10917660 on NIH RePORTER

What this research studies

This research investigates how vaping with 4th-generation e-cigarettes affects inflammation in individuals with asthma, particularly among Veterans and active-duty military personnel. The study aims to understand the potential toxic effects of e-cigarette aerosol on the airway inflammation associated with asthma, which is a common condition in these populations. By examining the inflammatory responses triggered by e-cigarette use, the research seeks to provide critical data that could inform public health policies and recommendations regarding vaping. Participants may undergo assessments of their respiratory health and inflammatory markers to evaluate the impact of e-cigarette exposure.

Who could benefit from this research

Good fit: Ideal candidates for this research are Veterans or active-duty military personnel who have a diagnosis of asthma and use e-cigarettes.

Not a fit: Patients who do not have asthma or do not use e-cigarettes may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and management of asthma exacerbations related to e-cigarette use, ultimately improving patient care and outcomes.

How similar studies have performed: While there is ongoing research into the effects of vaping, this specific investigation into the impact of 4th-generation e-cigarettes on asthma is relatively novel and untested.

Where this research is happening

San Diego, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Airway Disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.