Effects of 4th-generation e-cigarettes on asthma and inflammation
Official title: Immunomodulation and Inflammation Caused by 4th-generation E-cigarettes in the Setting of Asthma
Funded at VA San Diego Healthcare System · NIH-10917660 · Data updated 2026-11-12
This study is looking at how using new e-cigarettes might affect inflammation in the lungs of people with asthma, especially veterans and active-duty military members, to help understand the health risks of vaping for those with this condition.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | VA San Diego Healthcare System NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | October 1, 2024 |
| Project end | September 30, 2028 |
| Funding year | 2025 |
| NIH project number | 1I01BX006447-01A1 |
| Project ID | NIH-10917660 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Veterans or active-duty military personnel who have a diagnosis of asthma and use e-cigarettes.
✕Less likely to help
Patients who do not have asthma or do not use e-cigarettes may not receive any benefit from this research.
What this research studies
This research investigates how vaping with 4th-generation e-cigarettes affects inflammation in individuals with asthma, particularly among Veterans and active-duty military personnel. The study aims to understand the potential toxic effects of e-cigarette aerosol on the airway inflammation associated with asthma, which is a common condition in these populations. By examining the inflammatory responses triggered by e-cigarette use, the research seeks to provide critical data that could inform public health policies and recommendations regarding vaping. Participants may undergo assessments of their respiratory health and inflammatory markers to evaluate the impact of e-cigarette exposure.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of asthma exacerbations related to e-cigarette use, ultimately improving patient care and outcomes.
How similar studies have gone: While there is ongoing research into the effects of vaping, this specific investigation into the impact of 4th-generation e-cigarettes on asthma is relatively novel and untested.
Where this research is happening
-
VA San Diego Healthcare System
San Diego, United States Active
Researchers
- Principal investigator: Crotty Alexander, Laura Elise — VA San Diego Healthcare System
- Study coordinator: Crotty Alexander, Laura Elise
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.