Effectiveness of the HPV vaccine in women with HIV and its impact on cervical cancer screening
Official title: Real-world effectiveness of HPV vaccine in women living with HIV and its impact on cervical cancer screening accuracies
Funded at University of California Los Angeles · NIH-11080910 · Data updated 2026-11-12
This study is looking at how well the HPV vaccine works for women with HIV and how it affects their cervical cancer screenings, aiming to find better ways to keep them healthy.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project start | May 1, 2023 |
| Project end | April 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $109,771 |
| NIH project number | 5R01CA281293-03 |
| Project ID | NIH-11080910 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are women living with HIV, particularly those who are young or have been vaccinated against HPV.
✕Less likely to help
Patients who are not living with HIV or who have not received the HPV vaccine may not benefit from this research.
What this research studies
This research investigates how effective the HPV vaccine is for women living with HIV, particularly focusing on its real-world impact on cervical cancer screening accuracy. The study aims to evaluate the effectiveness of the vaccine and explore new screening methods that could improve outcomes for these women. By collaborating with the Pediatric HIV/AIDS Cohort Study, the research will analyze data to understand the relationship between vaccination and cervical cancer screening results. This approach seeks to address the unique challenges faced by women living with HIV in terms of cervical cancer risk and screening.
Why it matters
Potential benefit: If successful, this research could lead to improved cervical cancer prevention strategies for women living with HIV.
How similar studies have gone: Previous studies have shown promise in improving cervical cancer screening methods for women living with HIV, indicating that this research builds on existing knowledge.
Where this research is happening
-
University of California Los Angeles
Los Angeles, United States Active
Researchers
- Principal investigator: Moscicki, Anna-Barbara — University of California Los Angeles
- Study coordinator: Moscicki, Anna-Barbara
Related research
Other NIH-funded projects on the same topics.
-
mSaada: a mobile tool to boost cervical cancer screening in western Kenya
A mobile app helps community health volunteers manage cervical cancer screening tasks and follow-up for women in low-resource areas.
-
HPV self-collection in HIV care to screen for cervical cancer in Ethiopia
A patient-centered program tests a simple HPV self-collection approach within HIV clinics in Ethiopia to help detect cervical cancer earlier.
-
HOPE-inG: Increasing cervical cancer screening for women with HIV in Ghana
A study tests a home-based HPV self-sampling approach plus a tailored communication plan to help women living with HIV in Ghana get screened more often for cervical cancer.
-
CODA-based cervical cancer screening for LMICs using CRISPR and fluorescence
A low-resource, rapid test called CODA uses CRISPR and light signals to detect cervical cancer markers in women in sub-Saharan Africa to improve screening.
-
CODA-based cervical cancer screening in low-resource settings
A new, quick, low-cost test using CRISPR and fluorescence readouts to help screen for cervical cancer in women in sub-Saharan Africa.
-
CATSystem: a digital tool to boost cervical cancer screening and follow-up in Kenya
A digital tracking system helps doctors and patients in Kenya improve cervical cancer screening, treatment referrals, and follow-up, especially for women living with HIV.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.