Effectiveness of GLP-1 medications for treating type 2 diabetes in young people

Real-world Effectiveness and Utilization of Glucagon-Like Peptide-1 Receptor Agonists for Treatment of Type 2 Diabetes in Adolescents and Young Adults

NIH-funded research Children's Hosp of Philadelphia · NIH-10825007

This study looks at how well a type of diabetes medication called GLP-1 receptor agonists works for teenagers and young adults with type 2 diabetes, while also exploring the challenges they face in getting the treatment they need.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionChildren's Hosp of Philadelphia NIH-funded
Lab location1 site (Philadelphia, United States)
Project IDNIH-10825007 on NIH RePORTER

What this research studies

This research investigates how effective glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are for managing type 2 diabetes in adolescents and young adults. It aims to understand their real-world usage compared to other diabetes treatments, particularly focusing on the challenges faced by young patients, including access issues and health disparities. By analyzing data from a large electronic health record database, the study will provide insights into how these medications perform in everyday clinical settings for younger populations.

Who could benefit from this research

Good fit: Ideal candidates for this research are adolescents and young adults aged 17 to 40 who are diagnosed with type 2 diabetes.

Not a fit: Patients who are not diagnosed with type 2 diabetes or are older than 40 years may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could improve treatment options and outcomes for young people with type 2 diabetes.

How similar studies have performed: Previous research has shown promising results with GLP-1 RAs in adult populations, but this specific focus on adolescents and young adults is relatively novel.

Where this research is happening

Philadelphia, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.