Early warning systems to spot disorders in children and adults
Early Warning Systems for Childhood and Adult Disorders
This project develops ways to read natural biochemical rhythms in people to spot risk for childhood and adult disorders long before symptoms appear.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Icahn School of Medicine at Mount Sinai NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11306006 on NIH RePORTER |
What this research studies
You would be part of work that measures natural biochemical rhythms in the body—such as hormone cycles, temperature, and other chemical markers—by taking repeated samples or using wearable monitors. The team plans to create a new framework and technologies for sampling and analyzing these time-based signals so abnormal patterns can be recognized years before clinical signs. The research combines lab measurements, new sampling devices, and advanced data analysis to find biochemical signatures tied to later disease. Some participation may involve giving blood or saliva, wearing monitors, or sharing health history at Mount Sinai.
Who could benefit from this research
Good fit: Ideal candidates would be children or adults with early-life environmental exposures, a family history of chronic disease, or interest in long-term monitoring who can provide samples or wear monitoring devices.
Not a fit: People with advanced, symptomatic disease seeking immediate treatment are unlikely to receive direct benefit from this early-detection research.
Why it matters
Potential benefit: If successful, this approach could let doctors predict, prevent, or treat some diseases far earlier than is currently possible.
How similar studies have performed: Some related rhythm-based monitoring (for example sleep or hormone cycles and wearables) shows promise, but using high-resolution biochemical rhythms as an early-warning system for many disorders is largely novel.
Where this research is happening
New York, United States
- Icahn School of Medicine at Mount Sinai — New York, United States (Active)
Researchers
- Principal investigator: Arora, Manish — Icahn School of Medicine at Mount Sinai
- Study coordinator: Arora, Manish
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.