Early pancreatic cancer detection center
Clinical Validation Center for Early Detection of Pancreatic Cancer
This project works with hospitals to collect blood, tissue and imaging from people at higher risk to find and confirm tests that can detect pancreatic cancer earlier.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11388314 on NIH RePORTER |
What this research studies
Our team collects high-quality blood, tissue, and imaging samples from people with pancreatic cysts, new-onset diabetes, genetic risk, early-stage pancreatic cancer, and other benign pancreatic conditions across multiple hospitals. Samples and clinical data are compared in blinded, multi-institution analyses so researchers can compare biomarker panels (including CA19-9 and autoantibodies) and imaging approaches. The center standardizes specimen handling, links samples to detailed clinical follow-up, and shares annotated biospecimens for collaborative validation work. The effort aims to validate tests for use in at-risk patients and to build a resource for future early-detection research.
Who could benefit from this research
Good fit: Ideal participants are people at increased risk—such as those with certain genetic mutations, mucinous pancreatic cysts, or new-onset diabetes—who can provide blood or tissue samples and clinical follow-up.
Not a fit: People without pancreatic disease or risk factors, or those unable to travel to participating centers, are unlikely to benefit directly from this project.
Why it matters
Potential benefit: If successful, this work could produce validated tests that find pancreatic cancer earlier when treatment options work better.
How similar studies have performed: Earlier multi-center efforts, including a Phase 3 pre-diagnostic biomarker study and a blinded 'biomarker bakeoff,' produced promising leads but broader validation across sites is still needed.
Where this research is happening
New York, United States
- New York University School of Medicine — New York, United States (Active)
Researchers
- Principal investigator: Maitra, Anirban — New York University School of Medicine
- Study coordinator: Maitra, Anirban
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.