Early hardship and drug-use risk in low-income rural children

Early Adversity and Drug Use Vulnerability Among Low Income Rural Children: Testing a Neuro-ecological Model of Resilience

NIH-funded research University of Georgia · NIH-11261225

This project looks at how hardships in early childhood affect brain development and later risk for drug use in low-income rural children starting at age seven.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Georgia NIH-funded
Lab location1 site (Athens, United States)
Project IDNIH-11261225 on NIH RePORTER

What this research studies

You and your child would join a long-term study that links brain measures, thinking skills, behavior, and home and neighborhood stressors to later drug-use risk. Researchers will bring children in for brain scans, cognitive and emotional tests, and collect detailed information from caregivers about family and community experiences. The team will follow children over several years to see which brain and environmental patterns predict higher or lower risk for substance use. The aim is to find protective factors and guide prevention efforts tailored to rural communities.

Who could benefit from this research

Good fit: Children around age 7 from low-income families living in rural Georgia, along with their caregivers, are the ideal participants.

Not a fit: Children who live in urban areas, adults, or those without early-life poverty or adversity are unlikely to benefit directly from this particular study.

Why it matters

Potential benefit: If successful, this work could help identify children at higher risk and support earlier, community-tailored prevention to reduce future drug misuse.

How similar studies have performed: Previous studies have linked childhood adversity and brain changes to substance risk, but integrating brain scans with detailed rural environmental data in a long-term study is relatively novel.

Where this research is happening

Athens, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.