Early detection and types of cerebral visual impairment in young children
Integrative Neurodevelopmental Approach to CVI: Screening and Subtyping in Early Childhood
['FUNDING_R01'] · CINCINNATI CHILDRENS HOSP MED CTR · NIH-11310154
A new screening method will help find cerebral visual impairment in infants and toddlers so children can get help earlier.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CINCINNATI CHILDRENS HOSP MED CTR (nih funded) |
| Locations | 1 site (CINCINNATI, UNITED STATES) |
| Trial ID | NIH-11310154 on ClinicalTrials.gov |
What this research studies
Your child would be screened at three early ages between about 4 and 12 months using a new screening algorithm designed for infants. Children identified with possible cerebral visual impairment will have standardized vision and developmental testing at two follow-up visits to map how vision relates to motor, language, and cognitive skills. The team aims to define different neurodevelopmental profiles (subtypes) of CVI to guide more personalized interventions. This work is led by an interdisciplinary clinical team at Cincinnati Children's Hospital with pediatric vision and development expertise.
Who could benefit from this research
Good fit: Infants and young children (especially those around 4–12 months corrected age) at risk for or suspected of cerebral visual impairment, including those with a history of acquired brain injury or developmental concerns.
Not a fit: Children whose vision problems are due to eye-specific conditions (not brain-related processing) or older children outside the early-childhood window may not benefit from this early screening approach.
Why it matters
Potential benefit: If successful, children with CVI could be identified much earlier and receive targeted interventions to improve motor, language, and learning outcomes.
How similar studies have performed: Smaller prior studies support early detection of vision problems, but combining a multi-timepoint infant screening algorithm with standardized neurodevelopmental subtyping is a relatively new approach.
Where this research is happening
CINCINNATI, UNITED STATES
- CINCINNATI CHILDRENS HOSP MED CTR — CINCINNATI, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: SHAH, VEERAL SHAILESH — CINCINNATI CHILDRENS HOSP MED CTR
- Study coordinator: SHAH, VEERAL SHAILESH
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Acquired brain injury